BI110 Chapter Notes - Chapter 16: Extracellular Matrix, Microfibril, Cell Adhesion
Document Summary
Composed of fibers embedded in gel-like matrix, anchors cells, role in cell communication, regulate movement of substances into & out of cell: cell wall; bacteria, fungi, plants, some archaea. Provides support + structure: extracellular matrix (ecm); animals and protozoan cells. Ecm: composed of collagen, proteoglycans & other proteins that link cells and ecm, collagen: glycoprotein constitutes 40% of total amount of protein in human body forms fibers that integrate into network of proteoglycans (core is polysaccharide) Protein branch from polysaccharide smaller carbohydrates branch from protein: proteoglycans. Very hydrophilic & form gel-like colloid around exterior of cell: glycoproteins (aka fibronectins) Associate with c & p, also with proteins called integrins (embedded into plasma membrane)- transmit messages b/w mf & ecm. Help cells attach & move through ecm inner side of plasma membrane, integrins interact w/ proteins connected to microfilaments. Specialized ecm: basal lamina: specialized ecm that serves different functions in different tissues. Muscle tissues= bl surrounds muscle fibers strength.