Physiology 2130 Chapter Notes -Ketone, Myelin, Citric Acid Cycle
10 Apr 2014
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Gastrointestinal: (pg 343): fat, sources of fat: Saturated fat (bad, lard, butter); unsaturated fat (good, vegetable oil) Some fat digestion (lingual lipase is active, gastric lipase digest fat) not very effective b/c fat floats ontop of water. Pancreatic lipase: digest! (bile + colipase helps digestion!: bile + colipase keeps fat droplets dispersed (small droplets) . Micelle is coated in bile; colipase separates bile molecules and allow pancreatic lipase to gest them. Bile: both hydrophobic and hydrophilic: hydrophobic side associate with lipid; hydrophilic associate with water: enzyme mechanism: triglyeride --> monoglyceride + 2 free fatty acids (lipase/colipase, absorption: Fatty acids are hydrophobic so they can go through membrane. Cholesterol needs a transporter to be absorbed by intestinal cells. Both fatty acids and cholesterol are packaged into chylomicron (fat droplet coated in protein) to make it aqeous. Absorbed with lipids, transport into body as chylomicron (. : lymph then blood: water soluble: vitamin c and b (except b12)
