Health Sciences 3840A/B Chapter Notes - Chapter 5: Economic Evaluation, Decision Analysis, Clinical Trial
7 Jan 2020
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Chapter 5: measuring and valuing effects: health gain: some basics: Measurement of health effects: can be improvements in the main health outcome of interest (survival) or other effects, side effects of therapy for example. Data comes from both randomized controlled trials and observational data sets: registries, administrative databases, clinical series and long-term epidemiological studies. Randomized controlled trials are the best source for estimates of relative clinical effect: comparing 2 or more therapies, can be sometimes obtained from observational studies when no relevant trails are available. Estimates of some effects like rare side effects or effects that only become apparent in the long term are usually obtained from observational studies since these studies tend to have long-term follow up. Identification and measurement of health effects can also be important in the estimation of costs: a bleeding complication not only has important impacts on the health of the patient but also requires health care resources to treat.
