Biology 1002B Chapter Notes - Chapter 7: Rubik'S Revenge, Transfer Rna, Wobble Base Pair

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2 May 2020
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The consequences of errors in transcription are less severe(ernstig) than those of errors in dna. Translation mrna is decoded in sets of three nucleotides. 3 triplets encode stop codons (not amino acid) Amino acids can be coded by different triplets. Genetic code is redundant (=several codons for one amino acid) Genetic code is universal (=all organisms use the same code for the same amino acid) Need a punctuation signal to indicate the correct reading frame. Linear sequence 9 (+- 80 nucleotides) folds into cloverleaf" structure via base- pairing. Cloverleaf" structure further folds into a l-shape molecule with two free ends: anticodon and amino acid attachment site. During folding, intron like sequences are spliced out from the primary transcript by specialized enzymes. Up to about 10% of the bases are chemically modified to altered base versions of a, c, g, and u.

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