Biology 1002B Chapter Notes - Chapter Outcomes: Crispr, Genome Editing, Cas9
2 May 2019
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10:33 am identify definition of the "minimal genome". basic process for creating "three parent babies". Mitochondria are in eggs from mother -> mitochondria are defected -> kids will get this. Take parents embryo -> removed parents nucleus from cell of unhealthy mitochondria -> place in donor embryo basic process for cloning animals by somatic cell nuclear transfer (scnt). Take skin cell from embryo role of epigenetic barriers in animal cloning. example of cloned animals. basic mechanism for crispr cas9 genome editing. Tracer rna associates with cas9 to make a complex. Cas9 targets the viral dna and cuts the double stranded dna fundamental ethic issues arising from human genome editing. Not ethical ok for people in the future. Decisions we make now might affect something in the future estimate of number of genes necessary to sustain independent life. Use viral vector to deliver the trans gene for a specific tissue. Remove stem cells from people -> transform them -> reintroduce them.
