Biology 1002B Chapter 42.7: Ch. 42.7

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Researchers isolate mutants that affect developmental processes and identify the. The fruit y is a model system for this experiment. Gene expression = regulating determination & differentiation: ex: somites (blocks of messoderm cells) differentiate under genetic control, into skeletal muscle cells, nearby cells induce signals that express myod (regulatory gene), myod regulates transcription of. Myod, which helps to determine the function of somite cells: converts somites to myoblasts (undifferentiated muscle cells, myod regulates myogenin and mef genes, both regulatory genes. Leads to transcription that turns on another set of genes: the product of these genes promote differentiation of myoblasts into speci c muscle cells (ex: skeletal, cardiac etc. ) Determination/ differentiation usually depends on regulatory genes, which encodes for regulatory proteins. Regulatory genes are master regulators , which inturn is controlled by induction. Gene control of pattern formation: developing a body.

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