Biochemistry 2280A Chapter Notes - Chapter 10: Atp Synthase, Ion Channel, Alkene

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erinimpala672

4 Jul 2020

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Coa and nadh: 1st 3 work to convert pyruvate to acetyl-coa, enzymes: Latter 2 regulate the actions of pdh: pyruvate dehydrogenase (pdh, oxidizes pyruvate, creating o2, yields co2, 2 remaining c bind to thiamine pyrophosphate (vitamin. Coa, and citrate: step 2 -> citrate isomerized to isocitrate, aconitase. Isomerizes citrate -> isocitrate: step 3 -> -ketoglutarate and co2 formation. Isocitrate dehydrogenase: oxidizes and decarboxylates isocitrate -> form -ketoglutarate, generates the 1st co2 + nadh of cycle. Inhibited b atp + nadh + succinyl-coa: step 5 -> succinate formation, succinyl-coa synthetase, hydrolyzes the thioester bond in succinyl-coa -> form succinate + coa- Inhibitors -> atp, nadh, succinyl-coa, citrate: no activators. Inhibitors -> atp, nadh: activators -> adp, nad, -ketoglutarate complex. Inhibitors -> atp, nadh, succinyl-coa: activators -> adp, ca2+ 11. 4 oxidative phosphorylation: process which atp is generated via harnessing the h+ gradient and utilizes atp synthase to do so, proton-motive force, electrochemical gradient generated by etc across inner mitochondrial membrane.

Related Questions

2. In many cases, cellular signal transduction is mediated by a membrane-associated G-protein complex. Which is not right about this protein complex?

A) The complex is made of Î±-, Î²-, and Î³-subunit.

B) The G_sÎ±-subunit has a GTPase activity.

C) Depending on the receptor types, either G_sÎ±-subunit or G_iÎ±-subunit is used.

D) Signal transduction through G-proteins ultimately regulates protein phosphorylation.

E) None of the above.

3. Which statement is not right about the pyruvate dehydrogenase?

A) This enzyme is located in the mitochondria.

B) This enzyme consists of three different enzymatic subunits (E1, E2, and E3).

C) This enzyme catalyzes the reaction: Pyruvate + CoA + NAD Â® Acetyl-CoA + CO₂ + NADH

D) This enzyme also uses TPP (thiamine pyrophosphate), lipoic acid, and FAD as cofactors.

E) Despite its complexity, this enzyme is not an important regulation point of TCA cycle.

4. To maintain a proper rate of the TCA cycle, oxaloacetate is replenished periodically. To increase [oxaloacetate], ___X____ is turned on but the TCA cycled is turned off by phosphorylation of __Y__.

A) X = Glyoxylate cycle :::::: Y = isocitrate dehydrogenase

B) X = Glyoxylate cycle :::::: Y = isocitrate lyase

C) X = Q cycle :::::: Y = isocitrate dehydrogenase

D) X = Q cycle :::::: Y = isocitrate lyase

E) None of the above.

5. Assume you have three NADH and one FADH₂. Calculate the total numbers of H⁺ pumped into the inter-membrane space and the maximal number of ATP produced inside the matrix.

A) 40 H⁺ and 12 ATP
B) 40 H⁺ and 11 ATP
C) 36 H⁺ and 12 ATP

D) 36 H⁺ and 11 ATP
E) None of the above.

1. Which is an w-3 fatty acid?

A) B) C) D) E) None ofthese

2. In many cases, cellular signal transduction is mediated by amembrane-associated G-protein complex. Which is not right aboutthis protein complex?

A) The complex is made of Î±-, Î²-, and Î³-subunit.

B) The G_sÎ±-subunit has a GTPase activity.

C) Depending on the receptor types, eitherG_sÎ±-subunit or G_iÎ±-subunit is used.

D) Signal transduction through G-proteins ultimately regulatesprotein phosphorylation.

E) None of the above.

3. Which statement is not right about the pyruvatedehydrogenase?

A) This enzyme is located in the mitochondria.

B) This enzyme consists of three different enzymatic subunits(E1, E2, and E3).

C) This enzyme catalyzes the reaction: Pyruvate + CoA + NAD Â®Acetyl-CoA + CO₂ + NADH

D) This enzyme also uses TPP (thiamine pyrophosphate), lipoicacid, and FAD as cofactors.

E) Despite its complexity, this enzyme is not an importantregulation point of TCA cycle.

4. To maintain a proper rate of the TCA cycle, oxaloacetate isreplenished periodically. To increase [oxaloacetate], ___X____ isturned on but the rest step of TCA cycled is turned off byphosphorylation of __Y__.

A) X = Glyoxylate cycle :::::: Y = isocitrate dehydrogenase

B) X = Glyoxylate cycle :::::: Y = isocitrate lyase

C) X = Qcycle :::::: Y = isocitrate dehydrogenase

D) X = Qcycle :::::: Y = isocitrate lyase

E) None of the above.

5. Assume you have three NADH and one FADH₂.Calculate the total numbers of H⁺ pumped into theinter-membrane space and the maximal number of ATP produced insidethe matrix.

A) 40 H⁺ and 12 ATP
B) 40 H⁺ and 11 ATP
C) 36 H⁺ and 12 ATP

D) 36 H⁺ and 11 ATP
E) None of the above.

I put the following

1. D

2. D

3. E.

4. idk

5. idk

Can someone help me out for 4 & 5 and reassure I got 1-3correct! Thanks

sangriarabbit412

Biochemistry 2280A Chapter Notes - Chapter 10: Atp Synthase, Ion Channel, Alkene

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