Biochemistry 2280A Chapter Notes - Chapter 6: Covalent Bond, Osmosis, Net Force

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Reading 6: small molecules in cells (sept. 26th 2017) Fatty acid chains are components of cell membranes: fatty acids have 6 times more energy than glucose. If free, the carboxyl on the end of a fatty acid can be ionized: more often though it will form a group with an ester or amide. Phospholipids: hydrophobic fatty acid tails, hydrophilic heads (phosphate group and a small polar group). Lipid aggregates: fatty acids can form a surface film or small spherical micelles, triacylglycerols can form fat droplets in cytoplasm, phospholipids and glycolipids can form a self-sealing lipid bilayer. Steroids: common multiple-ring structure, e. g. cholesterol and testosterone. Interact with hydrophobic tails of lipid molecules: composed largely of hydrophobic side chains, peptide bonds holding the chains together are hydrophilic, atoms forming the backbone hydrogen bond to each other due to lack of water. Larger uncharged polar molecules hardly ever cross: charged molecules, are unable to cross regardless of their size.

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