Biochemistry 2280A Chapter Notes - Chapter 7: Regulatory Sequence, Long Non-Coding Rna, Transcriptional Regulation
15 Jan 2017
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Document Summary
Central dogma (information flow): dna -> rna -> proteins. Process by which information in dna is translated to a product (rna or protein) that has some effect on a cell or organism. If the rna is the final product (rrna, trna, mirnas, etc) it does not need to be translated for gene expression to take place (already done at that step) Many identical rnas copies can be made from the same gene. Next rna can start before the first one finishes fast! Rna chain is made by complementary base-pairing with the dna template. Rna transcript is the dna template complement. Does not remain hydrogen bonded to the dna after it is formed. Ribonucleoside triphosphates (atp, gtp, utp, ctp) provide energy. Prone to making more mistakes than dna-polymerase. Carry information transcribed from one gene, codes for a single protein (euk)/set of proteins (prok) Form structural and catalytic core of ribosomes.
