BIOL 150B Chapter Notes - Chapter 6: Radiant Energy, Competitive Inhibition, Kinetic Energy

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Simple control circuit: the product of a pathways inhibits the rst enzyme that begins the pathways. Too little substrate active sites not lled as often as possible. Too much substrate not enough active sites available: temperature: each enzyme has an optimal temperature at which its reaction rate is the greatest. Temperature rate of enzyme reaction. Temperature too much enzyme denatures: ph: each enzyme has an optimal ph at which its reaction rate is greatest. Extreme ph enzyme denatures: cofactors: non-protein helpers. Metals: inorganic (e. g. zinc, iron, copper: inhibitors & activators: Non-competitive inhibitor: does not enter the active site, but binds else where, changing the shape of active site so the substrate is unable to: an example of negative feedback. Allosteric regulation: either activates or inhibits allosteric enzymes: allosteric enzymes: switch between active & inactive forms, allosteric inhibition: stabilizes an enzyme in its inactive form, allosteric activation: stabilizes an enzyme in its active form.

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