NFS382H1 Chapter Notes - Chapter 2: Zinc Sulfate, Failure To Thrive, Anthropometry

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The objective of this study was to determine whether zinc deficiency is one of the factors involved in nutritional failure to thrive in infants and toddlers. Evidence to this effect was derived from the results of zinc supplementation studies in young children with low growth percentiles from low income families in denver- possibly malnourished kids. Within carefully controlled conditions, dietary supplementation with small quantities of zinc was associated with significant improvement in linear growth when compared with placebo-treated control children. In the zinc-deficient children, growth rates had typically started to decline in infancy. The pattern of decline at that time was characteristic of nutritional failure to thrive, with weight-for-age percentiles declining before linear growth was affected. The objective of the present study was to test these hypotheses by determining the growth response to dietary zinc supplementation of infants and toddlers from the same population with declining weight percentiles resulting in failure to thrive.

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