HMB265H1 Chapter Notes - Chapter 16: Exonuclease, Peptide, Transposase

• School: UTSG
• Department: Human Biology
• Course: HMB265H1
• Professor: Maria Papaconstantinou

Document Summary

Hmb265 lecture 16 readings - transposable elements (pg. Dna segments that can jump/transpose from place to place in genome. Certain tes insert themselves into particular genes _ not others. If jumps into gene can disrupt gene function = mutation. = mutation rates vary from gene to gene. Tes move after making a copy of themselves. Copy gets inserted into different chromosomal location, initial version stays. = here have exception to general rule that rate of reversion slower than rate of forward mutation. Transposition: type of sequence rearrangement w/ significant genomic impact. Move small pieces of dna (tes) from one position to another. Findings contradicted classical recombination that genes located at fixed position. Transposable elements are classified according to how they move. Te = any piece of dna that evolves ability to move from place to place within genome. Can have selfish tes (don"t do anything for host, just carry information that allow self- perpetuation)