PSYC62H3 Chapter Notes - Chapter 6: Haloperidol, Benzoylecgonine, Imipramine
Document Summary
Psyc62 chapter 6: psychostimulants: psychostimulants: drugs that increase psychomotor and sympathetic nervous system activity as well as improve alertness and positive mood, aka. I: cathinones, bath salts: synthetically produced cathinones, can contain any variety of synthetic cathinones (methcathinones, methylenedioxypyrovalerone, methylone, mephedrone, cathinones make up approx. Included information on coca plants, ancient human use, effects observed in animals, a(cid:374)d f(cid:396)eud"s own self-reports. Clara rebello: other administration routes result in poorer absorption. Methamphetamine administration produces psychostimulant effects from both methamphetamine and amphetamine: cathinone metabolism in the liver produces the active metabolite norephedrine (d optical isomer of pseudoephedrine) Clara rebello: cathinone and synthetic cathinones (like mephedrone and methylone) may inhibit reuptake of dopamine, norepinephrine, and serotonin, cocaine prevents monoamine reuptake by blocking the membrane transporters for dopamine, norepinephrine, and serotonin. Increases transport of dopamine into synaptic vesicles: may provide more stored dopamine for release, active metabolite cocaethylene also functions as a dopamine reuptake inhibitor.