PSYA01H3 Chapter Notes - Chapter 2.5: Critical Role, Reuptake, Mptp

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2 Apr 2017
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Many drugs that affect the nervous system operate by increasing, interfering with, or mimicking the manufacture or function of neurotransmitters. Agonists drugs that increase the action of a neurotransmitter. Antagonists drugs that block the function of a neurotransmitter. Some drugs alter a step in the production or release of the neurotransmitter, whereas others have a chemical structure so similar to a neurotransmitter that the drug is able to bind to that neuron"s receptor. If, by binding to a receptor, a drug activates the neurotransmitter, it is an agonist; if it blocks the action of the neurotransmitter, it is an antagonist. L-dopa is used to treat parkinson"s disease a movement disorder characterized by tremors and difficulty initiating movement and caused by the loss of neurons that use the neurotransmitter dopamine. Dopamine is created in neurons by a modification of a common molecule called l-dopa.

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