NROC69H3 Chapter Notes - Chapter 0: Amygdala, Perforant Path, Basolateral Amygdala
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Compare a cells (mcherry), with c / a (endogenous c fos) Compare overlap of a-c vs. a-a: a&c: statistically independent populations of dg cells. Ca1 cells: not due to generalization (control: only mcherry no chr2 i. e. no photo-activation did not show same effect -> is that a sufficent control?) Another control: chr2-yellow eyfp -> same freezing in a: off dox in a, back on dox placed in c, here they formed memories of both ctx a & c. But c not labelled, therefore can"t be activated. No in freezing in a this time in either a or c, regardless of whether animals exposed to c or not before fear conditioning. Possibly due to overlap of population of cells: but no diff in mice. Recap: worked in dg, not in ca1 cells. Next, examined induced memory recall of false memory by light reactivation of engram in dg: in distinct context d with light-off & light-on.
