HLTB21H3 Chapter : Malaria

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whiteduck976

25 Mar 2011

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Malaria: italian mal"aria (i. e. bad air), the great imitator. Oldest disease known to mankind that continues to have huge health consequence (50% global population at risk), found in chinese medical text nei chang . enlarged spleens, related malaria to ingestion of stagnant water roman fever. belief: resulting from poisonous vapours that emanate from roman campagna". William shakespeare: ague (english word for malaria) first to observe black-brown malaria pigments and mobile filaments emerging from clear spherical bodies in the red blood cells of infected blood, crescents in blood. haemoproteus: bird parasite closely related to malaria. Koch: fist to identify malaria parasite, argued that human malaria was caused by a mosquito bite but was unsuccessful. Ross and manson: discover the in the infectious stages in the mosquito salivary glands in sparrows, injects sporozoites (winner) Giovanni battista grassi: report that the anopheles claviger was the carrier of human malaria.

Related Questions

A person has been bitten by three mosquitoes over the past month and infected each time with malaria. The first time, the person was infected with drug-sensitive wild-type malaria. The second time the person was bitten with chloroquine-resistant malaria, and the third time with artemisinin-resistant malaria. Each infectious bite gave rise to a clonal population of malaria parasites. The population size of the drug-sensitive parasites is 10^9. The population of the chloroquine-resistant parasites is 10^7. The population of the artemisinin-resistant parasites is 10^7. What is the heterozygosity of the malaria parasites circulating within this individual host?

1. The three infectious diseases that cause the majority ofdeaths worldwide are influenza, hepatitis B, and malaria.

True False

Although it is normally transmitted by mosquitoes, malaria couldpotentially be transmitted by blood transfusions as the parasitethat causes it lives in the blood.

True

False

3. The overuse of ____________________ can cause bacteria todevelop genetic resistance.

4. Chagas is the most important parasitic illness in _______causing 40,000 deaths each year.

		Latin America
		Australia
		Asia
		Europe
		North America

5. List four factors that are responsible for emerginginfectious disease.

6. The Ebola virus is spread through casual contact.

True

False

tanpig844

QUESTION 15 (8 points)

Sickle-cell anemia is an interesting genetic disease. Normal homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Individuals homozygous for the sickle-cell trait (ss) have red blood cells that readily collapse when deoxygenated. Although malaria cannot grow in these red blood cells, individuals often die because of the genetic defect. However, individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. In addition, malaria cannot survive well within these "partially defective" red blood cells. Thus, heterozygotes tend to survive better than either of the homozygous conditions. If 9% of an African population is born with a severe form of sickle-cell anemia (ss), what percentage of the population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene?

HLTB21H3 Chapter : Malaria

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