PHA 3112 Chapter Notes - Chapter 32: Selective Serotonin Reuptake Inhibitor, Premenstrual Dysphoric Disorder, Posttraumatic Stress Disorder
10 Dec 2016
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Document Summary
Major depression: clinical features, pathogenesis, and treatment modalities. Depression: severe biologic illness; most common psychiatric disorder; suicide risk is high; underdiagnosed & undertreated. Clinical features: dsm-5 diagnostic criteria for a major depressive episode - Mnemonic: sad a faces: sleep disturbance; appetite change; depressed mood; anhedonia (loss of interest); fatigue; agitation/retardation; concentration; esteem feeling worthless; suicide. Loss of functioning: significant distress or impairment in social, occupational, etc. Rule out: not due to direct physiological effects of drug abuse, meds, or general condition. Dsm-5 diagnostic criteria for a major depressive episode. Major depression etiology/cause is complex & incompletely understood; some more vulnerable than other. Some healthy people get depressed unexpectedly w/o apparently cause; some by stressful life events. Vulnerable factors: heritage, a difficult childhood, chronic low self-esteem. Monoamine-deficiency hypothesis of depression: depression is caused by functional deficiency of monoamine neurotransmitters (norepinephrine, serotonin, or both; clinical observations made in 1960s. Baby blues: mild & transient symptoms; common & considered normal; treatment unnecessary.
