HSS 3305 Chapter Notes - Chapter 24: Nephrogenic Diabetes Insipidus, Diabetes Insipidus, Anterior Pituitary

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Pituitary hormones blood hormone levels exerts regulatory influences upon pituitary and hypothalamus which control amount of hormone synthesized and released by endocrine glands. Growth hormone overproduction caused by pituitary adenoma: causes gigantism in children and acromegaly in adults, may cause visual disturbances from tumor encroachment in optic chiasm. Actions controls rate of metabolic processes: required for normal growth and development of thyroid follicles, small amnt of unbound hormone to protein is physiologically active form of hormone. Major effects of hypothyroidism slow and lethargic: cardiovascular slow pulse, reduced cardiac output. 2: metabolic effects decreased metabolism, cold skin, weight gain, neuromuscular weakness, lassitude, sluggish reflex, mental/emotional mental processes sluggish and retarded, personality placid and phlegmatic, gastrointestinal constipation, general somatic cold, dry skin. T3/t4: some thyroid glands may be able to produce adequate hormone under normal circumstances but may be unable to increase its output in response to increased requirements w/o enlarging.

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