BCH 2333 Chapter Notes - Chapter 5: Intron, Ribosome, Lac Repressor

• School: University of Ottawa
• Department: Biochemistry
• Course: BCH 2333
• Professor: Christopher Boddy

Document Summary

Chapter 5: nucleic acids, gene expression, and recombinant dna technology. Dna"s base composition is governed by chargaff"s rules: dna has equal numbers of adenine and thymine residues (a=t) and equal numbers of guanine and cytosine residues (g=c) >on entering its host organism, dna is replicated to form a double-stranded molecule that obeys. Rna but not dna is susceptible to base-catalyzed hydrolysis: rna is highly susceptible to base-catalyzed hydrolysis, dna lacks 2"-oh groups so it is resistant to base-catalyzed hydrolysis so it is more stable then rna. Dna is the carrier of genetic information: transforming principle is dna. Transcriptional termination is a relatively simple process: site on the template strand where rna polymerase terminates transcription is governed by the base sequence, the control of transcriptional termination is not involved in the regulation of gene expression. Transfer rnas deliver amino acids to the ribosome.