ANP 1106 Chapter Notes - Chapter 15: Taste Receptor, Mechanoreceptor, Adenylyl Cyclase

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Chemical senses gustation (taste) and olfaction (smell); their chemoreceptors respond to chemicals in aqueous solution; taste to substances dissolved in saliva; smell to substances dissolved in fluids of the nasal membranes. Complement each other and respond to different classes of chemicals. Odorant bind to olfactory receptor neuron and generate ap. Olfactory epithelium: organ of smell, pseudostratified epithelium in roof of nasal cavity covering superior nasal conchae on each side of nasal septum. Smell is the o(cid:374)l(cid:455) i(cid:374)put pathwa(cid:455) to the (cid:272)ere(cid:271)ral (cid:272)orte(cid:454) that does(cid:374)(cid:859)t pass through thala(cid:373)us. Superficial location therefore damaged easily life span of 30-60 days; olfactory stem cells are at the base of epithelium and replace olfactory sensory neurons. Specificity of olfactory receptors an odor is made of hundreds of different chemicals: mucus captures airborne odorants (chemicals capable of detection by the receptors); there are ~1000 unique receptors capable of differentiating ~10 000 odors.

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