BIOL 200 Chapter Notes - Chapter 3: Detergent, Nucleosome, Guanine

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10 Dec 2017
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Topic 3. 1 nuclear structure & protein import: describe the structure of an interphase nucleus, and recognize structural elements in different kinds of microscopy. Double membrane: outer membrane is connected to er, w/ ribosomes attached. Nuclear pores: regulates material into / out of the cell. Nucleolus: dense region in the middle that has rrna transcription units, rrna synthesis, ribosomal subunits assembly (not a membranous organelle) Nuclear lamina: provides structural support, a meshwork of intermediate filaments. Chromatin: consists of dna and proteins (not condensed: describe the nuclear pore complex (npc) and explain the different types of nuclear transport mechanisms. Diffusion: molecules < 9nm can freely diffuse through the nuclear pore complex, not selective or energy-dependent (e. g. water, ions, small molecules. Active transport: mediated by receptors to transport large molecules by stretching the nuclear pores. Requirements: cargo proteins, receptor proteins, energy (gtp), and nuclear pore complex.

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