BIOL 112 Chapter Notes - Chapter 16: Adenine, Ribozyme, Aminoacyl-Trna
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BIOL 112 Full Course Notes
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Document Summary
Rna polymerase (preform template-directed synthesis from 5" 3" and no primer needed to begin transcription) synthesize mrna. Rna polymerase matches the base of ribonuculeotide triphosphate with a complementary base in gene (gene: section of dna that codes for a protein or rna) Rna polymerase catalyzes formation of phosphodiester bond between 3" end of growing mrna and the new ribonucleotide. Rna that is complementary to the gene is synthesized. * structure found by using: crystallography which allows biologists to obtain 3-d images of molecules. * shape: large, globular, many channels running through interior. * active site: located where several channels intersect. * dna fits into one of the enzyme"s channels two strands of dna in double-helix separate inside the enzyme to produce single stranded template at active site. Polymerase can"t do it on their own = sigma (detachable protein subunit) must bind to polymerase.
