KIN217 Chapter Notes - Chapter 16: Phosphoglycerate Kinase, Pyruvate Decarboxylase, Thiamine Pyrophosphate

• School: University of Waterloo
• Department: Kinesiology
• Course: KIN217
• Professor: Monica Vesely

Document Summary

Then alcohol dehydrog reduces acetaldehyde (organic compound) producing ethanol and nad+: lactate formed by lactate dehydrog also produces nad, much more energy can be extracted by converting pyruvate into acetyl coa (formed inside mito) Fructose and galactose are converted into glycolytic intermediates: fructose can take one of 2 pathways, much of ingested fructose is metabolized by liver using f-1-p pathway, fructokinase p. lates fructose to f-1-p, then split into glyceraldehydes and dihydroxyacetone phosphate. Lactose intolerance: deficiency of lactase enz, cleaves lactose into glucose and galactose. Glycolytic pathway tightly controlled: hexokinase, pfk, and pk are irreversible rxns that control glycolysis, pfk (muscle, high levels of atp allosterically inhibit this enz, amp reverses inhibition action of atp, dec in ph also inhibits, hexokinase (muscle) Inhibition of pfk leads to the inhibition of hexokinase: pyruvate kinase (muscle, atp inhibits, alanine (syn in step one from pyruvate) inhibits, pfk (liver)