BIOL 1080 Chapter 3ai: lecture 6 textbook notes
31 Jan 2017
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Synthesis and release of chemical messengers: amino acids (a. a) Can be obtained from the diet, the ones that function as neurotransmitters must be synthesized within the neuron that will secrete them. Following their synthesis in the cytosol they are transported into vesicles where they are stored until they are released in exocytosis. All are derived from a. a and all except thyroid hormones are synthesizes in the secretory cell by enzymes. The amine produced depends on the enzymes in the cell. Because dopamine is the precursor for all the other ones all the cells norepinephrine which is the precursor for epinephrine. that secrete this have tyrosine beta-hydroxylase and dopa decarboxylase both of which are found in the cytosol. After dopamine is synthesized it is transported into vesicles where its stored or used as a substrate from the next catecholamine: amines, catecholamines, serotonin, histamine.
