BIOC 2580 Chapter Notes -Hydrogen Bond, Amine, Acid Dissociation Constant

• School: University of Guelph
• Department: Biochemistry
• Course: BIOC 2580
• Professor: Pat Martin

Document Summary

Polarity and ionization 1. Synopsis: amino acid side chains may be classed according to polarity, hydrogen bonding ability and ionic properties. Biochemical reactions occur in aqueous solution at close to neutral ph. The behaviour of such groups is highly dependent on whether they are protonated or deprotonated. Review: chem*1040 notes regarding weak acids and bases. Amino acids with very non- polar side chains: ala, val, leu, ile, phe, met. These side chains are dominated by hydrocarbon, i. e. consists only of c- c and c- h bonds, e. g. These side chains are dominated by hydrocarbon, i. e. consists only of c- c and c- h bonds, e. g. valine. Hydrocarbon is non- polar and hydrophobic, or water avoiding. Polarity in a molecule have very different electronegativity. We say therefore that c=o and o- h are polar, while c- c and c- h are non- polar. Non- polar groups interact well with each other and poorly with polar groups.