BIOL207 Chapter Notes - Chapter 8: Lactase, The Transporter, Membrane Protein

• School: University of Alberta
• Department: Biology (Biological Sciences)
• Course: BIOL207
• Professor: John Locke

Document Summary

Introduction: la(cid:272)tose = (cid:862)(cid:373)ilk suga(cid:396)(cid:863, digested by lactase enzyme in small intestine, hydrolyses lactose into galactose and glucose and then imports them into cells via a second membrane protein called the sodium-glucose. How?: when the ribosome first binds to the mrna, both are floating free in the cytosol. In the lct mrna the lengths of the (cid:1009)"utr is (cid:1005)(cid:1005), (cid:272)odi(cid:374)g se(cid:395)ue(cid:374)(cid:272)e is (cid:1009)(cid:1011)(cid:1012)(cid:1008), a(cid:374)d (cid:1007)"utr is (cid:1008)(cid:1011)(cid:1013) (cid:374)u(cid:272)leotides. In humans, 65% of people follow the lct temporal gene expression and become lactose intolerant. These people raised milk animals that added an available food source. So people with the lp genes would have been favoured and had more kids and passed it on: mutations in the lct gene that produce a lactose persistence allele. Note the locations on genes are numbered relative to the first base pair read by the rna polymerase being +1.