BPK 140 Chapter Notes - Chapter 11: Anal Sex, Hematopoietic Stem Cell Transplantation, Sub-Saharan Africa
8 Sep 2017
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Disease = acquired immune deficiency syndrome (aids) Began in central africa where infected apes transmitted it to humans by biting them. Natural history of hiv/aids: virus enters body, infection: virus multiplies in t-cells (hard to find, symptoms of infection: non-specific (fever, fatigue, swollen lymph glands, viral concentrations build up to levels that will be contagious. Can start infecting others but undetectable: antibody response from immune system. Will test hiv-positive at this point (blood test to look at antibodies to hiv: appearance of symptoms of aids. Can infect many others without even knowing you are infectious. Prolonged and costly treatment (k/year: opportunistic infections, death. Stages in hiv infection: acute infection state (2-4 weeks) Cd4 immune cells produce large amounts of hiv which destroys them. High blood levels of hiv cause high risk of transmission to others: clinical latency stage (average of 10 years without therapy, or several years with. No hiv related symptoms or only mild ones.
