NSE 13A/B Chapter Notes - Chapter 11,13,14, 15: Thoracic Vertebrae, Inferior Oblique Muscle, Choroid
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This section discusses key points about structure and function related to pain. Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage. In terms of neuroanatomy, pain is a highly complex and subjective experience that originates from the central or peripheral nervous system, or both. Pain develops by nociceptive and neuropathic processing: nociceptive pain develops when nerve fibres in the peripheral and central nervous systems are functioning and intact. It starts outside the nervous system and results from actual or potential tissue injury. Nociception occurs in four phases: transduction, transmission, perception, and modulation. This pain typically is predictable and time limited based on the extent of the injury. Nociceptive pain can be further classified as somatic or visceral. Somatic nociceptive pain can be superficial (derived from the skin surface and subcutaneous tissues) or deep (derived from joints, tendons, muscles, or bone).