PHAR 100 Chapter Notes - Chapter 18: Pneumocystis Jirovecii, Selman Waksman, Beta-Lactamase
11 Nov 2016
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Lesson d. 1 antibacterial, antifungal, antiviral and antimalarial agents. Describe the history of introduction of antibiotics. Describe the mechanism of action of penicillin. Describe the properties of selected penicillin"s and cephalosporin. Describe the properties of ciprofloxacin, erythromycin, tetracyclines, chloramphenicol and aminoglycosides. Describe the current method for treating tuberculosis. Describe the rationale for the combination of trimethoprim with sulfamethoxazole. Describe the properties of antiviral agents, paying special attention to the life cycle of. Hiv and the rational design of drugs to combat it. Describe the advantages and disadvantages of the use of antibiotic combinations. General principles of the use of antimicrobial agents. Describe the life cycle of the malaria parasite and the drugs available to combat the parasite. Paul ehrlich (germany, 1854) introduced the concept of chemotherapy; designed organoarsenical drugs which lead to the creation of the cyphilis cure. Gerhard domagk (germany, 1930s) synthesized sulfonamide drugs, used efficacious against a variety of bacterial diseases.
