PHAR 100 Chapter Notes - Chapter 13: Acetaldehyde Dehydrogenase, Blood Alcohol Content, Aldehyde Dehydrogenase
11 Nov 2016
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Document Summary
State the properties of ethanol in terms of absorption, distribution and biotransformation. State the effects of various blood alcohol concentrations on central nervous system functions. State the proposed mechanism of neuronal inhibition of ethonal. State the effects of ethanol on the central nervous system, cardiovascular system, gi tract and liver in terms of short-term and chronic use. List the effects of ethanol on the developing fetus. List the effects of ethanol on driving. One of the three most used non-medical drugs in canada. Produces more health problems and deaths than all illicit drugs combined. Was first used as a sedative hypnotic drug. Fermented beverages can be traced back to 8000 bc (mead was prepared from honey) Ten to 13ml of absolute alcohol is the amount metabolized by the liver each hour. Ethanol is absorbed rapidly from the stomach and upper small intestine. Rate is influenced by: stomach-emptying time, ethanol concentration in the gi tract.
