BIOL 205 Chapter Notes -Group Ii Intron, Small Nuclear Rna, Ribozyme
Document Summary
Group i: e. g. tetrahymena rrna (tom cech: no sequence conservation at splice junction, carry conserved sequences internally, introns self-splice (rna catalysis, ribozymes, guanosine as cofactor, transesterifications, no external energy input. Splicesome-mediated splicing: gu found at 5" intron-exon junction, ag marks 3" intron-exon junction, a is part of branch site (consensus longer than this, intron ends up as lariat, no particular order in which introns are removed. Complex patterns of eukaryotic mrna splicing tropomyosin gene. U1 or u2 small nuclear rna (snrna) bind with protein to form small nuclear ribonucleoprotein particles (snps) U4 and u6 base pair causes u6 to replace u1 at 5" exon-intron boundary. Sebastian m. fica, nicole tuttle, thaddeus novak, nan-sheng li, jun lu, Prakash koodathingal, qing dai, jonathan p. staley & joseph a. piccirilli. In nuclear pre-messenger rna splicing, introns are excised by the spliceosome, a dynamic machine composed of both proteins and small nuclear rnas (snrnas).
