BIOL 205 Chapter Notes -Thomas Cech, Mirn21, Francis Crick
Document Summary
1900-1925 devoted to proving chromosomes were hereditary material. Late 1980"s projecting strategies! all the letters freely available to everyone in every country! Synthetic biology: construction of dna to build organisms that can perform tasks. "artificial life" breakthrough announced by scientists may 20th , 2010. Artificial life, the stuff of dreams and nightmares, has arrived. Rnai (double-stranded rna) dsrna inhibits the gene to which it is made- degradation and block! Micro rnas: short rnas have emerged as a new means of diagnosing and treating disease, block translation of mrna into protein, initiate breakdown of normal mrna, microrna- Some up or down regulate a single gene. Others regulate multiple gene networks microrna-21 initiates and maintains tumours in vivo. Nature, 2 september 2010 microrna-21 (mir-21) is overexpressed in most types of human cancer, but no experiments have demonstrated a causal role for this microrna in tumourigenesis.
