NURSING 3PA2 Chapter Notes - Chapter n/a: Glucose Tolerance Test, Corticosteroid, Esophagus

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Female hormones: hypothalamic neurosecretory cells release gnrh at puberty, binds to anterior pituitary cells (gonadotrops) to stimulate secretion of fsh and lh. Inhibin: from granulosa cells of follicles, feedback for hpo axis with estrogen and progesterone. Changes in pregnancy: 12 weeks: can palpate uterus above pelvic bone during exam, can auscultate heartbeat using. 12%, co increased 30-40% peaking at 24 weeks, blood volume increases 40-50% with disproportional increase in plasma that can lead to physiological anemia, increased aldosterone, Infertility: failure to achieve pregnancy after 1yr (6mo if >35), ~8. 5%, 40% females, 30-40% males, 10- Increased hormones: ovarian dysfunction (tumors, pcos: decreased hormones, high gonadotropin: menopause, congenital ovarian failure (gonadal dysgenesis, resistance to gonadotropins, premature ovarian failure, acquired ovarian failure due to autoimmune disease, chemo, environmental toxins) Low: secondary ovarian failure (hyperprolactinemia, hpo axis disorders, functional hypothalamic-anovulation due to starvation, hypothyroidism or psychogenic disturbance) Low or normal: excess testosterone, pcos, ovarian tumour, excess dheas, adrenal tumours, congenital adrenal hyperplasia, excess progesterone.

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