MEDRADSC 2Z03 Chapter Notes - Chapter 8: Stainless Steel, Radiation Protection, Lead Shielding

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Radioisotope processing equipment and automated synthesis modules are usually installed in shielded workstations or hot-cells to protect personnel from exposure to radiation. Radiation shielding is made from dense materials such as concrete and heavy metals such as lead. For pet, hot-cells are usually constructed of lead (around 75 to 100 mm thickness) supported by a steel structure and clad with stainless steel. The stainless steel provides a smooth and chemically resistant surface that is easily cleaned. Hot-cells have special ventilation that provides clean air to the work zone within whilst maintaining a clean environment for radiopharmaceutical synthesis. The ventilation also keeps the hot-cell at a negative pressure so that any airborne radioactive material cannot escape outside and into the laboratory environment. Rather, airborne contaminants are mostly removed by special filters located in the ventilation ducting. Hot-cells are usually equipped with services such as power, compressed air and inert gases that are used to support radiopharmaceutical synthesis.

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