MEDRADSC 1B03 Chapter Notes - Chapter 2: Cellular Adaptation, Hypertrophy, Hyperplasia

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Five ways cells may adapt to change: atrophy. Decrease in the size of an organ or body part due to the shrinkage in the size of its cells. Due to reduced use, insufficient nutrition and aging. Example: shrinkage of muscle after a cast, reproductive organs during menopause, hypertrophy. Increase in the size of an organ/ tissue mass increase in the size of the existing cells due to an. Results from an increased workload on the organ/ body part. Example: increased size of muscle due to exercise, increased kidney size in uni kidney compensatory hypertrophy, increase in heart size due to increased myocardial size due to increased workload, hyperplasia. Increase in the size of an organ/ mass due to an increase in the number of cells. Only occurs in cells capable of mitosis (not nervous or muscle tissue) 2: breast tissue & uterine endometrium during pregnancy, liver regeneration after partial hepatectomy, metaplasia.

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