HTHSCI 2HH3 Chapter Notes - Chapter 2: Interspinous Ligament, Diplococcus, Spinal Canal
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Central Nervous Infections
Diagnostic Tools
CT Scans: imaging method used to demonstrate pathological or psychological alterations of living tissue,
good tool for imaging dense material
MRIs: best for non-calcified tissue
Lumbar puncture: procedure to collect a sample of cerebral spinal fluid for cytological, biochemical, and
microbiological analysis
Blood Brain Barrier: restricts the entry of most substances into the CNS, prevents antimicrobial drugs
from entering the CNS
Disseminated Intravascular Coagulation: purple rash in individuals with sepsis caused by the disordered
coagulation as a result of abnormally sustained generation of thrombin
Headache: difficulty turning the head horizontally shows a positive sign of jolt accentuation
Bacterial Meningitis
• Fever and neck stiffness
• Sudden onset with high severity
• Disseminated intravascular coagulation
Lumbar Puncture
• Invasive technique performed under aseptic conditions
• Clinical specimens should be obtained before antimicrobial therapy has begun to avoid the loss
of viable pathogen necessary for laboratory diagnosis
• 3 tubes of 1Ml, chemistry, microbiology, cytology
Equipment
• Skin disinfectant
• Sterile gauze
• Lumbar puncture needle
• Sterile screw-cap tubes
• Syringe and needle
• Transport container
Technique
• Patient must be completely still either sitting up or laying on their side, with their back arched
forward so their head almost touches their knees
1. Disinfect skin with alcohol to remove debris and oil
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Document Summary
Ct scans: imaging method used to demonstrate pathological or psychological alterations of living tissue, good tool for imaging dense material. Lumbar puncture: procedure to collect a sample of cerebral spinal fluid for cytological, biochemical, and microbiological analysis. Blood brain barrier: restricts the entry of most substances into the cns, prevents antimicrobial drugs from entering the cns. Disseminated intravascular coagulation: purple rash in individuals with sepsis caused by the disordered coagulation as a result of abnormally sustained generation of thrombin. Headache: difficulty turning the head horizontally shows a positive sign of jolt accentuation. Bacterial meningitis: fever and neck stiffness, sudden onset with high severity, disseminated intravascular coagulation. Invasive technique performed under aseptic conditions: clinical specimens should be obtained before antimicrobial therapy has begun to avoid the loss of viable pathogen necessary for laboratory diagnosis, 3 tubes of 1ml, chemistry, microbiology, cytology. Lumbar puncture needle: sterile screw-cap tubes, syringe and needle, transport container.