BIOLOGY 2A03 Chapter 5: Chapter 5 Cell Communication
19 Jan 2016
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Then binds to receptors on target cells: neurotransmitters. Very short distance the neurotransmitter needs to move. Detect intercellular messengers and convert them into a meaningful intracellular response. Four features: specificity: signal molecule fits in its receptor while others do not, amplification: 1 receptor binding can lead to. 1,000,000 intracellular signals: desensitization/adaptation: feedback can, integration: the intracellular signal can be the result of integration of. These ion channels respond more slowly to messenger binding, due to the time required for the alpha subunit to be activated and bind the channel. In this case, the channel itself does not act as the receptor: other g-protein linked receptors regulate enzymes that produce second messengers (e. g. , cyclic amp, camp", g-proteins can be stimulatory (gs) or inhibitory (gi) Second messenger systems can amplify intercellular the signal from the messenger ( first messenger": e. g. g-protein receptor regulating camp production by adenylate cyclase; the type of receptor bound by adrenaline, the -adrenergic receptor)
