BIOCHEM 2EE3 Chapter Notes - Chapter 25: Aminoacyl Trna Synthetase, Aminoacyl-Trna, Francis Crick

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Chapter 25 information decoding: translation and port translational protein processing. Uga, uaa, uag) in normal circumstances, aminoacyl-trna will not have a complementary anticodon and translation will stop; these are commonly used to stop translation of a message: the code is 2 things, degenerate: reduntant; usually. Glu to val = changing gaa glu codon to a gua. Val codon: green = usual start; red = stop codons, the wobble hypothesis, aa in codons can usually be identified using the first 2 codon letters and the third letter will express redundancy, ex. Thr: one trna can recognize many diff codons. I(cid:374) the i(cid:373)age: g i(cid:374) the 5" a(cid:374)ti(cid:272)odo(cid:374) (cid:272)a(cid:374) pair (cid:449)ith either c or u i(cid:374) the (cid:272)odo(cid:374) (this depends on orientation: sometimes one trna cannot translate multiple codons, ex. 4/6 leu codons start with cu and are translated by 2 trnas using wobble. But the other 2 codons will need a diff anticodon to be translated.

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