PSYC 311 Chapter Notes - Chapter 18.5: Opioid Receptor, Cue Reactivity, Injective Function
9 Jun 2016
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Administration of crh can reinstate drug-taking behaviour and administration of a drug that bocks crh receptors can reduce the likelihood of relapse from drugs or drug cues. Crh receptors in the vta appear to be especially important. Infusing crh into the vta causes relapse, and infusion of crh receptor antagonists prevents reinstatement of drug-taking by stressful stimulus. This section covers the most important drugs in terms of popularity and potential for addiction. Opiate addiction has several high personal and social costs. First, heroin is illegal in most countries, so the user becomes a criminal. Second, because of tolerance, a person must take increasing amounts of the drug, and as this habit becomes more and more expensive, it can lead to crime to support the addiction. Third, an opiate addict often uses unsanitary needles, and substantial percentage of people who inject drugs have been exposed to hepatitis or aids.
