PSYC 311 Chapter Notes - Chapter 16.3: Schizophrenia, Flu Season, Genetic Disorder

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The negative and cognitive symptoms are very different to the positive symptoms of schizophrenia. The symptoms are similar to those produced by brain damage caused by several different means: evidence suggests that these symptoms of schizophrenia are a product of brain abnormalities, esp. in the pfc. Most patients with schizophrenia exhibit neurological symptoms that suggest the presence of brain damage- in particular, the symptoms categorized as negative and cognitive symptoms. Many studies have found evidence of loss of brain tissue in ct and mri scans of schizophrenic patients: e. g. The relative ventricle size of the schizophrenic patients was found to be more than twice the size as that of control subjects. The most likely cause of the enlarged ventricles is a loss of brain tissue; thus, the scans provide evidence that chronic schizophrenia is associated with brain abnormalities: e. g. It has been found that the loss of grey matter with age in schizophrenics is greater than in controls.

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