PSYC-233 Chapter Notes - Chapter 7.2: Pharmacotherapy, Gien, Libido

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1 Nov 2016
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Neurotransmitters and the withdraw system (bis);critical links to emotionality temperament and neuroticism( predicts anxiety) trait. Clonginger said harm avoidance system (equiv. to bis) mediated by serotonin. One allele of gene associated with high anxiety (serotonin relates inversely to harm avoidance) Neurotransmitter receptors adjust (ie high levels of serotonin lower receptor sensitivity, and vice versa); some people need more of one nt to do the same process. Fenfluramine: releases serotonin and prevents reuptake [chain reaction: hypothalamus releases prolactin to counteract the serotonin] ; overtime drugs adjust receptor sensitivity (ie anxious people have an excess of serotonin, which drugs adjust receptor sensitivity) Third system: sensation seeking: zuckerman sensation seeking described as desiring experience (faster drivers, > drug use, extreme sports, >anti-social behaviour, dissatisfied with commitment relationships) Role of enzyme mao (oxidase) which regulates serotonin and dopamine, mao also linked to aggression, impulsivity, dominance, sociability.

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