HLSC-128 Chapter Notes - Chapter 10: Immunoglobulin G, Thymus, Endoplasmic Reticulum
19 Oct 2016
School
Department
Course
Professor
Document Summary
Human physiology: from cells to systems (3rd canadian ed. Local vasodilation causing redness and heat: release of histamine on mast cells, vasodilation occurs in the arterioles, then the capillaries, blood velocity slows. Increase in blood volume to the site brings more phagocytic leukocytes and plasma proteins. Permeability increases: enlarges capillary pores, plasma proteins are able to escape the blood vessel. Local oedema: raises local interstitial fluid-colloid osmotic pressure. Increased local capillary blood flow (blood pressure: fluid is pushed out of the capillaries, causes swelling. Walling off of inflamed area: the conversion of fibrinogen into fibrin, the injured region is walled off to prevent the spread of infection and the spread of other harmful products. Leukocyte migration: neutrophils arrive at the site of injury first and later monocytes. Once they leave the blood stream they can never return: selectins (a type of cell adhesion molecules) protrude form the inner epithelial lining of the capillary.
