CHEM 271 Chapter Notes - Chapter 7: Functional Magnetic Resonance Imaging, Monod-Wyman-Changeux Model, Reactive Oxygen Species

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Chapter 7 portrait of a protein in action. Hemoglobin, which is contained in red blood cells, eiciently carrying oxygen from the lungs to the issues while also contribuing to the transport of carbon dioxide and hydrogen ions back to the lungs. Bind oxygen cooperaively, meaning that the binding of oxygen to a site in one chain increases the likelihood that the remaining chains will bind oxygen. Oxygen binding properies are modulated by the binding of hydrogen ions and carbon dioxide in a manner that enhances oxygen-carrying capacity. Myoglobin, located in the muscle, facilitates the difusion of oxygen through the cell for the generaion of cellular energy and provides a reserve supply of oxygen available in ime of need. Consists largely of helices that are linked to one another by turns to form a globular structure. Myoglobin and hemoglobin bind oxygen at iron atoms in heme.