CHEM 271 Chapter 18: Chapter 18

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The first step of oxidative phosphorylation is the electron transport chain (the transport of electron from. 18. 1: eukaryotic oxidative phosphorylation takes place in mitochondria. Recall: biochemical purpose of citric acid cycle, which takes place in the mitochondria, is to generate high-energy electrons. Oxidative phosphorylation will convert those electrons into atp and also takes place in the mitochondria. Hence there are two compartments of the mitochondria: The matrix is where most of the citric acid cycle and fatty acid oxidation takes place. Oxidative phosphorylation, however, occurs in the inner mitochondrial membrane. Inner membrane has a cytoplasmic side and a matrix side. The electron-transfer potential of an electron is measured as redox potential. In oxidative phosphorylation, the electron transfer potential of. Nadh or fadh2 is converted into the phosphoryl-transfer potential of atp. The measure of phosphoryl- tra(cid:374)sfer pote(cid:374)tial is gi(cid:448)e(cid:374) (cid:271)y g " (seen previously). The corresponding value for electron- transfer potential is e0" (cid:894)redu(cid:272)tio(cid:374) potential).

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