BIOL 261 Chapter 4: chapter 4 notes
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Chapter 4 mapping eukaryote chromosomes by recombination (only intro, 4. 1, 4. 2 & 4. 5) A genes position can be used to define it at the dna level. In turn, the dna sequence of a wild-type gene or its mutant allele is a necessary part of deducing its underlying function: the genes present and their arrangement on chromosomes are often slightly different in related species. Geneticists can deduce the evolutionary genetic mechanisms through which these genomes diverged useful in interpreting mechanisms of evolution. The arrangement of genes on chromosomes is represented diagrammatically as a unidimensional chromosome map, showing gene positions, known as loci, and the distances between the loci based on some kind of scale. Recombination-based maps map the loci of genes that have been identified by mutant phenotypes showing single-gene inheritance. Physical maps show the genes as segments arranged along the long dna molecule that constitutes a chromosome.