CHEM 1004 Chapter Notes - Chapter 14: Corn Starch, Coal Tar, Osteoarthritis

• School: Carleton University
• Department: Chemistry
• Course: CHEM 1004
• Professor: Gerald Buchanan

Document Summary

Chapters 14 - non steroidal anti inflammatory drugs (nsaids) Most common use is the alleviation (relief) of pain. Also a antipyretic anti- inflammatory and alalgestic: advantage: Longer half life than ibuprofen (~12 hours) thus less frequent dosing i: also effective against menstrual pain and cramps, side effects of ibuprofen and naproxen include upset stomach, heartburn and dizziness. Y2k wonder drugs for osteoarthritis and rheumatoid arthritis. Much less likely to cause bleeding or stomach irritation than aspirin. Repurposing - find new use for drug that has already been approved. Botox is the only approved preventative treatment for people with chronic migraines (15 days a month of headaches, each last 4 hours) Can cause problems breathing swallowing or speaking. Toxins can spread away from injection site (most toxic substance known) Binders and fillers - all solid pill formations contain these. A pharmacologically inactive substance formulated with an active compound, ex. cellulose and cornstarch.