BSCI-1510 Study Guide - Midterm Guide: Cyclin D, E2F, Asteroid Family
2 Nov 2016
School
Department
Course
Professor
Document Summary
Allows dynamic equilibrium between heterochromatin and euchromatin depending on modification of heterochromatin. If didn"t stick out-would not be able to have dynamic chromatin. More h1-has to do with pulling together. Backbone of dna is negatively charged histone proteins must be positively charged. Changes how tightly dna associates with itself. All cells have same content dna and same content of genes. Histone modifying enzymes different from cell to cell. Alcohol dehydrogenase-even in same cell (liver) can switch back and forth when ingest alcohol. Cyclins normally degraded as fast as made. Window in time where cyclin-cdk comes together. Cyclin d puts first two phosphates on. Alteration in cyclin levels likely cause changes for misregulation of checkpoints. High level, probably go into next phase early-still full of mistakes. Gene in all of our cell types. Children have tumors in back of eye. Inherited one bad copy of gene and had one good copy.
