MICROBIO 101 Study Guide - Microorganism, Cycloserine, Biofilm
30 Oct 2014
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Study guide for lecture 15 microbiology 101 fall 2012. Antibiotic resistance- a property of some bacteria that can make them harder to kill with antibiotics. Dna gyrase- a protein that contributes to folding dna in a highly structured and packaged manner during dna replication. Intrinsic resistance- a bacteria isn"t susceptible to an antibiotic, maybe because it lacks the target, isn"t permeable, or pumps the antibiotic out. Acquired resistance- antibiotic resistance that is conferred to an organism due to a mutation or horizontal gene transfer. Lactamase- a method of inactivating antibiotics, a protein that breaks the bond of the beta lactam ring and causes problems with the antibiotic"s binding. Lactamase inhibitor- restores the susceptibility of bacterial cells that produce beta lactamase to beta lactam antibiotics. Pbp2"- penicillin binding protein, produced by meca- can still perform transpeptidase reactions but it does not bind to beta lactam drugs. Meca- produces pbp2", if produced in s. aureus cells it produces mrsa.
