BIOCHEM 501 : Part 4 Review
Document Summary
Theme 1: base pairing the molecular mechanism for transferring genetic information: dna agct & rna agcu, a-t(or u, g-c. Theme 3: nucleoprotein complex formation: complex aggregates of specific proteins form on dna leading to localized changes in. Dna twisting: these complexes often set the stage for major events such as the initiation of dna replication or the initiation of site specific recombination. Theme 4: phosphoryl transfer reactions: all enzymatic reactions that result in the polymerization of polynucleotides (rna or. Dna), the breakdown of polynucleotides or the recombination of polynucleotides involve the formation and/or breakage of phosphodiester bonds. All of these rxns proceed through a common catalytic mechanism call a phosphoryl transfer reaction. The function of the enzyme is to activate the oxygen that attacks the phosphate. Polynucleotide structure: pentose suger, 1" purine or pyrimidine base. Pyrimidines cytosine, thymine (dna), uracil (rna: 5" phosphate group that binds to 3" of another nucleotide in dna and rna.
