BIOL 2100 Midterm: Exam 5 Study Notes
Document Summary
Idea of genetic linkage: the particular alleles of different genes that are typically inherited together if those genes are close together on the same chromosome. Snp: single nucleotide polymorphism: one type of genetic marker. Str: short tandem repeat; more efficient than snp as genetic marker. Many tandem repeats throughout genes; tandem repeats have nothing to do with gene expression, but are different in individuals. Str: amplify tandem repeats in dna, more repeats, the larger the fragment. Multiplexing: testing for multiple different markers at the same time; primers can be another 100 base paris away; so products are 100 extra base pairs long, Using primers as florescent, different colors are available. Used by fbi for individually recognizing any individual on the planet. Specifically expressed in blood vessel cells early in development. Delta 21: deletion of 21 nucleotides, mutation in blood cells, 7 fewer amino acids, Dominant mutant: blocks function gene at that level; non-functional.
